منابع مشابه
Molecular Signatures in Urologic Tumors
Urologic tumors continue to represent a huge fraction of cancer cases in the United States, with over 376,310 estimated new diagnoses in 2013. As with many types of tumors, urologic tumors vary greatly in their phenotype, ranging from minimally invasive to malignancies possessing great metastatic potential. The increasing need for more efficient and less invasive methods of cancer detection, as...
متن کاملMolecular therapy in urologic oncology.
During recent years, significant advances have been made in the field of molecular therapy in urologic oncology, mainly for advanced renal cell carcinoma. In this hitherto largely treatment-refractory disease, several agents have been developed targeting the von Hippel-Lindau metabolic pathway which is involved in carcinogenesis and progression of the majority of renal cell carcinomas. Although...
متن کاملProgrammed Cell Death Protein 4 -Expression in Urologic Tumors
Introduction: To investigate the role of the tumor suppressor gene Pdcd4 (programmed cell death 4) in benign and malignant prostate tissue specimen. Materials and Methodology: Pdcd4 immunohistochemical expression was investigated in 73 prostate cancer and 14 normal tissues. The expression levels were correlated with clinicopathological parameters. Results: Both, cytoplasmic and nuclear Pdcd4 st...
متن کامل[De novo urologic tumors in kidney transplant patients].
CONTEXT The ability of a transplant recipient to accept a graft depends on the ability of immunosuppressive drugs to regulate the immune system. Such treatments have been associated with tumor promotion and progression. EVIDENCE ACQUISITION A systematic literature review was carried out. Electronic searches were performed in PubMed database. The searching criterion was "urological tumors in k...
متن کاملMolecular signatures of cell cycle transcripts in the pathogenesis of Glial tumors
BACKGROUND: Astrocytic brain tumors are among the most lethal and morbid tumors of adults, often occurring during the prime of life. These tumors form an interesting group of cancer to understand the molecular mechanism of pathogenesis. Histological grading of Astrocytoma based on WHO classification does not provide complete information on the proliferation potential and biological behavior of ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2013
ISSN: 1422-0067
DOI: 10.3390/ijms140918421